
Product Description
Nonapeptide-1Basic Information
Product Name | Nonapeptide-1 |
Synonyms/Alias | Melanostatine; Nonapeptide-1 |
CAS No. | 158563-45-2 |
Sequence | MPFRWFKPV |
Purity | ≥98% |
Molecular Formula | C61H87N15O9S |
Molecular Weight | 1206.52 |
References | Melanostatine 5 |
Storage | Common storage 2-8℃, long time storage -20℃. |
Package Size | 1g/10g /50g bottle, 500g/1Kg Foil Bag or customer requirement |
Payment Term | Trade Assurance, T/T, Western Union, L/C |
Delivery time | Around 1-3 working days after your payment |
Guarantee | Full refund if you met any quality problem |
Nonapeptide-1, also called Melanostatine-5, is a propriety peptide that was originally developed for its antimicrobial activities. Animal research has revealed, however, that nonapeptide-1 can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions. Animal models suggest that nonapeptide-1 can reduce synthesis of melanin and help decrease skin pigmentation to a substantial degree.
Nonapeptide-1 is of primary research interest for its ability to reduce hyperpigmentation by inhibiting the action of tyrosinase in melanin-producing cells. The ability to regulate melanin production has potential application in a number of conditions, including photodamage of the skin.
Research also suggests that nonapeptide-1 may play a role in the central nervous system where it may act on both dopaminergic receptors and opioid receptors to modify pain signaling as well as behavior. Studies in mice support the idea that nonapeptide-1 may have central actions that affect behavior and pain.
12Product Description
Hexapeptide-2
Basic Information
Product Name | Hexapeptide-2 |
Sequence | H-His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 |
CAS | 87616-84-0 |
Molecular Formula | C46H56N12O6 |
Molecular Weight | 873.01g/mol |
Source | Synthetic |
Storage | Common storage 2-8℃, long time storage -20℃. |
Package Size | 1g/10g bottle, 500g/1Kg Foil Bag or customer requirement |
Payment Term | Trade Assurance, T/T, Western Union, L/C |
Delivery time | Around 1-3 working days after your payment |
Guarantee | Full refund if you met any quality problem |
What is Hexapeptide-2?
Hexapeptide-2 is a skin lightening peptide to brighten skin and even-out skin tone. This peptide obtained by synthesis acts as an antagonist to α-MSH. The binding of α-MSH to its receptors mediates skin pigmentation. It competes for α-MSH binding to its receptors, thereby decreasing melanin synthesis. Hexapeptide-2 induces a decrease in the melanin content in epidermal cells.
Function of Hexapeptide-2
1. Skin whitening & freckle removing.
2. Reducing the accumulation of melanin.
3. Effectively improve skin color, fade melanin, from inside to outside whitening, firming skin.
4. Redefine Dermal Elasticity.
5. Increase Facial Firmness.
6. Essential Proteins Enhance Skin-tightening Collagen.
13Product Description
Tetrapeptide-30
Basic Information
Product name |
Tetrapeptide-30 |
CAS NO. |
1036207-61-0 |
Synonyms |
Tetrapeptide-30 |
Category |
Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Cosmetic peptide. |
Purity |
98% Tetrapeptide-30 |
Appearance |
Tetrapeptide-30 Powder |
Shelf life |
2 years |
Usage |
Tetrapeptide-30 provides anti-inflammatory activity. It can prevent melanin synthesis by preventing activation of the tyrosinase. This product can be applied in various types of whitening or spot corrective products. |
Storage |
Tetrapeptide-30 should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
Package Size |
1g/10g /50g bottle, 500g/1Kg Foil Bag or customer requirement |
What is Tetrapeptide-30 ?
Tetrapeptide-30 is a new peptide developed to balance skin tone. There are various mechanisms to brighten skin tone, including reducing or inhibiting tyrosinase activity, blocking melanin transfer into keratinocytes, and inhibition of melanocyte activation. It is theorized that Tetrapeptide-30 Solution works by reducing the amount of tyrosinase and inhibiting melanocyte activation.
Function of Tetrapeptide-30
1. Visibly diminishes hyperchromatic spots.2. Improves evenness of skin tone.
3. Reduces lesions and melasma on ethnic skin.
4. Active on all kinds of skin types.
5. Provides significant anti-inflammatory effect.
6. Skin-friendly.
7. Safely inhibits the pigmentation process.
14Product Description
Name:Decapeptide-12
Customized: Customized
Suitable for: Adult
Purity: >99%
Usage: Pharmaceutical Intermediates
MF:C65H90N18O17
MW:1395.55
CAS: 827306-88-7
Powder: Yes
State: Solid
Purity (HPLC): 99.0%
Appearance: White Powder
What is Decapeptide-12
Decapeptide-12 reversibly binds to tyrosinase, an enzyme found in a number of different pigment-producing cells. It prevents tyrosinase from catalyzing the oxidation of phenols, the first step in melanin production. In mammals, tyrosinase is found only in melanosomes, special compartments within pigment-producing cells.
Tyrosinase is not preserved across species and, in fact, can differ drastically in structure even among closely-related species. In humans, differences in the efficiency of tyrosinase determine skin color and are the result of slight modifications in the TYR gene found on chromosome 11 .
Decapeptide-12 is approximately 17 times more potent than previous treatments for hyperpigmentation, including hydroquinone . Studies in cultured melanocytes over 7 days demonstrated a 27%-43% reduction in melanin content .
Decapeptide-12 has undergone multiple animal trials and may eventually be included in commercial products for treating hyperpigmentation.
Function of Decapeptide-12
Decapeptide-12 reduces the appearance of hyperpigmentation-age spots, sun spots, uneven skin tone and photo damage-without the typical side effects of other brighteners like irritation and redness. Plus, soothing antioxidants like licorice root also ease sensitive skin.
Decapeptide-12 reduces the appearance of hyperpigmentation-age spots, sun spots, uneven skin tone and photo damage-without the typical side effects of other brighteners like irritation and redness. Plus, soothing antioxidants like licorice root also ease sensitive skin.
The rapidly growing field of targeted tumor therapy often utilizes an antibody, sometimes tagged with a tumor-ablating material such as radioisotope, directed against a specific molecule. This report describes the discovery of nine novel decapeptides which can be radioactively labeled, bind to, and deliver P to colon cancer cells. The decapeptides vary from one another by one to three amino acids and demonstrate vastly different binding abilities. The most avidly binding decapeptide can permanently deliver very high levels of radioisotope to the adenocarcinoma cancer cell lines at an efficiency 35 to 150 times greater than to a variety of other cell types, including cell lines derived from other types of cancer or from normal tissue. This experimental approach represents a new example of a strategy, termed peptide binding therapy, for the potential treatment of colorectal and other adenocarcinomas.